NOW SERVING Psychedelic Culture

Dr. James Cooke

Discovering New Psychedelic Drugs

As our ancestors foraged for mushrooms or drank beer made from ergot-infested barley, they stumbled upon substances that can have the most profound effect on the mind.  Ancient ritual use developed, sacraments were lauded, mother nature’s gift was revered. 

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What Do Ayahuasca Visions Really Mean?

Ayahuasca is a powerful, indigenous plant medicine preparation that contains psychedelic DMT and several other psychoactive substances.  The visions that ayahuasca produces can be astounding and life-changing but is there any pattern to these visions or are they just the chaotic hallucinations of a drug-addled brain? What is an ayahuasca experience like? When we flood

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The Cosmic Giggle: Laughter and Psychedelics

Some psychedelic experiences feel sacred and profound while others leave us howling with laughter. Laughter is a common experience on psychedelics, from psilocybin mushrooms to cannabis.  Why is this?  Why are these mind-altering substances capable of tickling us in this way?  And is there a link between the profound metaphysical insights that psychedelics can occasion

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Does the Universe Have a Purpose?

A common experience for psychonauts is of feeling as though they have discovered some previously hidden meaning and purpose in the universe.  Many who undergo psychedelic experiences come away feeling as if everything happens for a reason, that there is a grand logic underlying existence.  This is an idea that philosophy and religions have explored

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The Brain’s Psychedelic System

Naturally-occurring psychedelics co-evolved with us. Rather than acting to scramble our brain activity in some chaotic way, psychedelics actually activate a pre-existing pathway in our brain.  Psychedelics do this by connecting to the serotonin 2A receptor, also known as the 5HT2A receptor. Why do psychedelics do this and what is this pathway for?  Does the DMT

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