Slavia's Blueprint

Salvia Divinorum Guide: Effects, Uses, Legality and Safety

Jump to Section

Jump to Section

Salvia divinorum is a perennial herb with psychedelic properties found in the mint family (Lamiaceae). This family contains many commonly-used edible herbs such as basil, rosemary, oregano, sage, thyme, and lavender. Besides simply “Salvia”, S. divinorum is known by many common names in the West, including Diviner’s Sage, Lady Salvia, Sally-D, and Magic Mint. 

Salvia is found around the world today, but it has been used traditionally for centuries by the Mazatec people in the Sierra Mazateca region of Oaxaca, Mexico. Here, the Mazatec shamans use the plant for divination and healing in ritualistic ceremonies. The Mazatec refer to the plant as “ska Pastora” or “hojas de la Pastora”, meaning “leaves of the Shepherdess.”

Since the early 90s, it has become available in the psychedelic culture around the world, commonly consumed by smoking the dry leaves and various extracts (5x, 10x, etc.).

Table of Contents

  1. Overview
  2. History
  3. Legality
  4. Pharmacology
  5. Effects
  6. Uses
  7. Salvia Today
  8. Salvia FAQ

1. Overview 

What is Salvia?

Salvia divinorum is a flowering plant endemic to the Mazatec areas of the Sierra Madre Oriental in Oaxaca, Mexico. It grows in the humid, high tropical mountains at an elevation between 300 and 800 meters.

Like the other large varieties in the mint family, the Salvia plant can grow to heights exceeding one meter. It’s characterized by large green leaves, hollow square stems, white flowers (which bloom rarely), and violet calyxes. The plant rarely sets viable seed and reproduces vegetatively. Because of its limited geographical habitat, it is one of the rarest psychoactive plants on Earth. However, today it is widely cultivated in the United States and around the world. 

Salvia Divinorum

The genus name of Salvia has its origins in the Latin word salvere, meaning “to be saved” or “to be well”, which reflects the wide array of medicinal properties found throughout the genus. The species name divinorum was given in reference to its traditional use in divination and healing. 

Salvia divinorum is loosely translated as “Seer’s Sage” or “Diviner’s Sage.” However, the Swiss chemist Albert Hofmann criticized the Latin name of the species. In a 1984 interview with the Czech psychiatrist Stanislav Grof, he stated, 

“It is a wrong name, bad Latin; it should be actually Salvia divinatorum. They do not know very good Latin, these botanists. I was not very happy with the name because Salvia divinorum means “Salvia of the ghosts”, whereas Salvia divinatorum, the correct name, means “Salvia of the priests”, But it is now in the botanical literature under the name Salvia divinorum.” 

As we’ll explore later, Dr. Hofmann (along with his wife Anita and the famous ethnomycologist R. Gordon Wasson) was among the first to travel to southern Mexico to collect S. divinorum specimens for identification purposes in the early 1960s.

Other Types of Salvia

There are over one thousand varieties of plants in the Salvia genus, but only S. divinorum possesses hallucinogenic properties. Many other salvia species are used for ornamental purposes or as herbal remedies. In this section, we will overview some of the other common Salvia species.

Salvia officinalis 

Salvia oficinalis is commonly known as Garden Sage. It is an aromatic, woody perennial shrub native to the Mediterranean region, but found in many places throughout the world. It has grayish leaves and blue to purplish flowers. Garden sage has a long history of medicinal and culinary use and is commonly used as an ornamental garden plant.

Salvia hispanica 

Commonly known as Chia, Salvia hispanica is a flowering plant endemic to central and southern Mexico and Guatemala. It’s an annual herb that grows up to 1.85 meters tall, characterized by clustered purple or white flowers. It is mostly known and grown for its edible chia seeds. 

Salvia greggii

Commonly known as Autumn Sage, Salvia greggii is an herbaceous perennial native to the rocky areas of Texas and Mexico. Despite its name, it blooms throughout summer and autumn and produces a wide variety of flower colors. For this reason, it’s commonly hybridized with other closely-related Salvia species for ornamental purposes.

Salvia leucantha

Salvia leucantha, commonly Mexican Bush Sage, is a perennial herb native to the subtropical and tropical conifer forests of central and eastern Mexico. This low-maintenance species has high ornamental value, producing beautiful velvety flower spikes from late summer to early autumn.

Salvia nemorosa

Salvia nemorosa goes by the common names of Woodland Sage or Violet Sage. It is a clump-forming, hardy perennial with striking blue-violet flower spikes. Caradonna is endemic to central Europe and Western Asia but grows easily in other parts of the world. It is widely used as an ornamental garden plant.

Salvia farinacea

Salvia farinacea, or Mealycup sage, is a clump-forming perennial salvia native to Texas and Mexico. The plant flowers from June to frost, and is characterized by shiny leaves and violet-blue spikes. It is commonly cultivated as an annual plant and will attract hummingbirds and butterflies. 

Salvia apiana

Salvia apiana, or white sage, is an evergreen perennial shrub found in the southwestern United States and northwestern Mexico. It has white, evergreen leaves that release oils and resins with a strong aroma when rubbed. White sage has been used for centuries in rituals and ceremonies. It is often burned in these contexts for clearing negative energy from spaces. 

Salvia coccinea

Known commonly as scarlet sage, Salvia coccinea has been used for generations for medicinal, ornamental, and culinary reasons. It is commonly cultivated in gardens around the world and is known by its whorls of red flowers around its spikes.

Ways to Consume Salvia

There are four main ways to consume S. divinorum: smoking, chewing the leaves, making salvia infusions, and using sublingual tinctures. 

Smoking Salvia

Smoking is the most common method of consumption in the West, given the commercial availability of extract-enhanced dried leaves. Smoking Salvia leads to an intense, short-lasting trip. It is the most effective way to absorb salvinorin A, the psychoactive compound responsible for its effects. 

Salvia extracts and dried leaves can be smoked in a cigarette, pipe, bong, or vaporized. Usually only pure salvinorin A is vaporized, as is sometimes done in clinical trials. The smoke is inhaled quickly and deeply and held for at least 20-30 seconds. One quarter to one half of a gram of dried leaves constitutes a mid-level dose. A lesser amount is needed for extract-enhanced leaves, depending on the strength of the extract (for instance, 0.1-0.3 grams for 5x extract). 

Traditionally, salvia is administered by the Mazatec shamans in two ways: chewing the leaves and making a strained juice preparation. In either case, only fresh S. divinorum leaves are used.

Chewing Salvia

The chewing method involves rolling fresh leaves into a ball or cylinder called a quid. The quid is then chewed slowly once every 10 seconds, and kept under the tongue between chews. The quid and juice are held in the mouth for up to 30 minutes, then spat out or swallowed. With this method, salvinorin A is absorbed through the mucus membranes of the mouth. 

Salvia Infusions

Strained juice preparations are an infusion made by grinding the leaves, squeezing out the juice, and drinking it mixed with water. This method is the least common way of consumption. This is because they require significantly more leaves (20-80 fresh leaves) and the preparation is very bitter. In addition, salvinorin A is not well-absorbed in the GI tract.

Salvia Tinctures

Salvia tinctures are a purified liquid containing concentrated salvinorin A. These are consumed sublingually and offer a quicker onset of action compared to the quidding or infusion method. Salvia tinctures can be purchased commercially depending on regional legality. They can also be made at home from ground leaf material extracted in high-proof alcohol. 

2. History 

Indigenous Uses

Salvia divinorum has been used for centuries by the Mazatec shamans (curanderos and curanderas) in the Oaxaca region of Mexico. Similar to psilocybin mushrooms, the shamans use the plant for spiritual purposes, divination, and as a catalyst for knowing the causes of illnesses and the adequate cures for their patients. 

Unlike all-night psilocybin mushroom rituals, the Mazatec Salvia ceremonies typically last two to three hours. The ceremonies begin with prayers and blessings to Christian saints, the Holy Trinity, and the Virgin Mary. They take place in total, quiet darkness because the shamans see the salvia spirit as a timid deer that is scared away by bright lights and noises. At lower doses, it has been used traditionally by the shamans as a diuretic, to treat diarrhea, anemia, headaches, rheumatism, and the magical illness called “swollen belly.”

The deep history of the plant is not well known. Everything that is known dates to post-Spanish conquest, which explains why the names of the plant by the Mazatec center around Christian ideas. It is still not known whether S. divinorum is a wild plant native to the Sierra Mazateca region, or a cultigen of the Mazatecs or another indigenous group.

Modern Day Discovery

For hundreds of years, Mazatec shamans were the only ones with intimate knowledge of Salvia’s psychedelic properties. That situation changed in the late 1930s when a group of anthropologists led by Jean Basset Johnson came to the Mazatec region to study their culture. They were the first to document the hallucinogenic use of Salvia by the Mazatec shamans, who would brew the leaves into a tea they called “Hierba Maria.” This infusion was named from the shared visions the shamans would have of the Virgin Mary during the trip experience. Still today, the plant is seen by the Mazatec as the embodiment of the Virgin Mary.

Later in the early 1960s, Albert Hofmann, his wife Anita Hofmann, and the ethnomycologist R. Gordon Wasson traveled to the Sierra Mazateca region in search of the plant. R. Gordon Wasson believed it was a sacred entheogen called pipiltzintzintli used by the Aztecs, but this has since been a matter of debate among ethnobotanists. Gordon and Hofmann verified the psychoactivity of Salvia themselves and sent samples for identification to Carl Epling, a botanist working in the botanical department of Harvard. Here, Epling determined from their samples that it was a new species of salvia, which led to its naming of Salvia divinorum.

Later, in the 1990s, the psychoactive constituents were identified by a team led by the ethnobotanist Daniel Siebert, one of the leading experts on Salvia. Daniel Siebert did the first extraction of salvinorin A and was the first person to have a typical smoked salvia experience. 

Interest in S. divinorum has accelerated in the last decade in Europe and North America, in parallel with legislative attention. In the 1990s, it entered the commercial market largely as a smokable extract. As we’ll see, the legality of salvia is a continually shifting landscape, and many states and countries have now banned it.

3. Legality

Up until the early 2000s, the legality of Salvia was not an area of focus for legislators. However, with the commercialization of Salvia came enormous online visibility, especially on the emerging world of YouTube where individuals would post their (often bizarre) trip experiences. In the wake of a scare campaign by the media, initiatives were proposed to ban it in numerous states and throughout the world. 

Laws Passed

Beginning in 2005, a number of states in the United States have banned or limited its sale or possession. Currently, S. divinorum and/or salvinorin A is illegal in 33 states and the territory of Guam. Other states are currently considering legislation to ban the sale and/or possession of salvia. A complete listing is available here

Internationally, Salvia is currently illegal in these countries:

  • Armenia
  • Australia
  • Belgium
  • Canada
  • Croatia
  • Czech Republic
  • Denmark
  • Germany
  • Hong Kong
  • Italy
  • Japan
  • Latvia
  • Lithuania
  • Poland
  • Portugal
  • Ireland
  • Romania
  • South Korea
  • Sweden
  • Switzerland.

Where is Salvia Legal?

Barring certain city-level laws, salvia is currently legal in these states:

  • Arizona
  • California (18 years and older)
  • Oregon
  • Washington
  • Idaho
  • Montana
  • Nevada
  • New Mexico
  • Maine (18 years and older)
  • Utah
  • New York
  • New Jersey
  • New Hampshire
  • Massachusetts
  • Maryland (21 years and older)
  • South Carolina
  • Tennessee (legal for aesthetic, landscaping, or decorative purposes)
  • West Virginia
  • Wisconsin (possession only)

Internationally, Salvia is currently legal in:

  • Austria
  • Cyprus
  • France
  • Indonesia
  • Myanmar
  • Malaysia
  • Netherlands
  • Serbia
  • Slovenia
  • South Africa
  • Spain (possession and use only)
  • Thailand
  • Ukraine

In Estonia, Finland, Iceland, and Norway, Salvia is treated as a medicinal herb that requires a doctor’s prescription.

4. Pharmacology 

Salvinorin A

The leaves of S. divinorum contain over a dozen unique chemicals, the most potent being the Salvinorin A, a diterpenoid that accounts for its psychedelic effects. Salvinorin A is the most potent naturally-occurring hallucinogen, approximately 10 times as potent as psilocybin and half as potent as LSD. In terms of dosing, a threshold dose of purified salvinorin A is 200mcg, while a full-fledged psychedelic experience will be produced at approximately 1000mcg (1mg). According to a study by Daniel Siebert, the plant content of salvinorin A can vary but averages 0.245% of dried leaf material.

In contrast to the classic psychedelics, which produce their effects via the serotonin system by binding to 5-HT2A receptors, salvinorin A is a potent and highly selective κ-opioid receptor agonist. Thus, in humans given the opioid blocker naloxone, Salvia produces very little to no effects. κ-opioid receptors are involved in many processes in the mind and body. This includes bodily perception, motor control, mood, depression, addiction, pain, and perceptual distortions.

Salvinorin A is commonly referred to as an atypical psychedelic. Typical psychedelics contain nitrogen atoms in the molecular structure, but salvinorin A is uniquely a non-nitrogenous psychedelic with no structural similarity to the others. In addition, it’s currently the only known psychedelic diterpene and naturally-occurring κ-opioid receptor agonist.


Research on the toxicity of Salvia divinorum and salvinorin A are sparse, so further studies are warranted. Only one animal study has been conducted to examine the toxic side effects of salvinorin A. In this study, rats were chronically administered high doses of salvinorin A (up to 6400mcg) for two weeks. The researchers found little to no differences between the salvinorin A-administered group and the control group in post mortem histological studies. They concluded that salvinorin A possesses “relatively low toxicity”, even at doses many times greater what humans are exposed to. 

Overall, there is no evidence to support long-term toxic side effects associated with the recreational use of Salvia. In addition to no reported overdoses on Salvia, it does not appear to be physically addictive (in fact, it seems to be anti-addictive).


There are no known toxic drug interactions with Salvia divinorum. However, research is limited so it’s always best to exercise caution. While many people take regular medications alongside Salvia without problems, every individual reacts differently. Some combinations may lead to unexpected interactions, so it’s always best to start with a conservative dose and gauge the effects from there.


According to preliminary research and anecdotal reports, Salvia is generally recognized as safe and with low abuse potential. No case of fatal salvinorin A poisoning has been documented, and the LD-50 (median lethal dose) is presumed to be extremely high. 

Moreover, multiple studies have found that consumption of Salvia is associated with little to no adverse side effects. One study from 2013 investigated the dose-related effects of inhaled salvinorin A in 8 healthy adults. The researchers found no evidence of persisting adverse effects at a follow up one month later. 

The biggest risk associated with the drug is improper set and setting. During the short-lived trip, Salvia is known to impair coordination and create a loss of connection with consensus reality. The fast onset and intensity can lead to problems if not prepared for. For this reason, Salvia should never be smoked while driving or operating heavy machinery. It is always best to experiment with salvia with an experienced trip sitter in a relaxed and safe environment (i.e. optimal set and setting). 

Salvia should be avoided in individuals predisposed to or with a history of psychosis. There have been case study reports of acute psychosis and paranoia that has lasted for days in individuals predisposed to mental illness. 

5. Effects 

Depending on the dose and route of administration, a salvia trip may range from a warm, italicized version of everyday reality to a full-blown mystical experience. 

How Long Does Salvia Last?

When smoked, a Salvia high is characterized by a near-immediate onset and a short duration. When salvia leaves or sublingual tinctures are orally ingested, the effects are more gradual and last longer. 

OnsetDurationAfter Effects
Smoked/vaporized30-180 seconds5-30 minutes30-60 minutes
Chewed10-20 minutes30-90 minutes30-120 minutes
Sublingual (tincture)10-20 minutes30-90 minutes30-120 minutes


The strained juice or tea infusions have the longest duration of effects, lasting up to 3 hours. However, this method is not very efficient because much of the salvinorin A that is ingested is deactivated by the GI tract before reaching the bloodstream.

Physiological Effects

Physiological effects of salvia may include:

  • Dizziness
  • Perspiration
  • Slurred speech
  • Decreased heart rate
  • Chills
  • Difficulty maintaining balance
  • Uncontrolled walking or standing

Psychological Effects

At low doses, psychological effects may include:

  • Increased body awareness (enhanced interoception)
  • Experiencing one’s body as safe and trustworthy
  • Increased emotional awareness
  • Enhanced presence of mind
  • Creative, dreamlike states of consciousness
  • Heightened introspection
  • General alterations in perception

At high doses, common psychological effects include,

  • Ego dissolution
  • Synesthesia
  • Dissociation
  • Depersonalization
  • Entity contact
  • Changes in feelings of body ownership (merging with objects, feeling heavy or light)
  • Vestibular hallucinations (flying and/or floating in space)
  • Tactile hallucinations (sensation of being pushed, pulled, or stretched)
  • Open and closed eye visuals
  • Loss of awareness of surroundings
  • A sensation of entering alternate realities or dimensions

Common Side Effects

Like other psychedelics, Salvia has the potential to produce negative side effects that last the duration of the trip. This includes:

  • Fear, terror or panic
  • Confusion
  • Agitation
  • Abdominal pain 
  • Difficulty speaking
  • Changes in body temperature (flushing and sweating)
  • Headache
  • Nausea

Confusing, difficult, or frightening experiences appear to be more common in Salvia experiences compared to classic psychedelics, especially when high strength extracts are used. In this case, many users infrequently use Salvia, or even just have a single experience and stop there.

Salvia vs DMT

Salvinorin A and DMT are both entheogenic compounds often used in ritualistic settings for consciousness exploration and healing. DMT and Salvia may both be smoked, and both have a short effect duration, plateauing within a matter of minutes. Like other psychedelics, neither DMT or Salvia leads to physiological dependence.

Mechanistically, DMT and salvinorin A act on very different neural pathways. Similar to the other classic psychedelics, DMT is a serotonergic alkaloid that binds to 5-HT2A receptors. On the other hand, salvinorin A is a non-alkaloid psychedelic, acting instead on κ-opioid receptors. This accounts for the differences in effects.

Both DMT and Salvia produce profound ego-shattering experiences, leading to mystical breakthroughs that result in loss of self, space, and time. With that said, the subjective effects are different. Salvia is described as more visceral, fragmented, and sometimes bizarrely disconcerting due to the tactile and vestibular hallucinations. Sensations of being pushed sideways, stuck, or becoming objects are more characteristic of a Salvia trip.

A DMT experience is reported as more lucid and revelatory, like being propelled into a timeless “cosmic” energy or returning to a home that has been forgotten. Many people report DMT experiences are easier to integrate than Salvia experiences.

Salvia vs Weed

Salvia and cannabis are both plants and are commonly smoked, but the similarities mostly stop there. For one, Salvia and cannabis sport very different mechanisms of action. Weed alters mood and cognition by interacting with CB1 and CB2 cannabinoid receptors. On the other hand, the salvinorin A in Salvia selectively binds to (you guessed it) κ-opioid receptors. 

Unlike weed, which is much more mellow and lasts anywhere from 1-4 hours, Salvia is an intense, short-lived psychedelic experience at commonly-used dosages. Weed will not produce full-fledged hallucinogenic effects such as ego dissolution experiences, intense visual distortions, extracorporeal sensations, and contact with external entities and realities. All of the above are part and parcel of a Salvia trip. 

At very low doses, Salvia may share some effects with being stoned. This may include heightened awareness of bodily sensations, increases in sensual and aesthetic appreciation, novel perspectives or insights on problems, euphoria, and laughter. 

6. Uses 


Traditionally, Salvia has been used in ceremonial settings like psilocybin mushrooms, peyote, and ayahuasca. However, as a result of its commercialization and online visibility, the plant has been increasingly used as a recreational drug, particularly among youth and young adults. In the 1980s, it was reported to be used recreationally among teenagers in Mexico to get high. Similar to what has been seen in the United States, the teenagers would buy dried Salvia leaves and smoke them as a marijuana replacement. Today, smoking extracts of salvia appears to be the most common way of consumption among recreational users.

Because Salvia is a legalized hallucinogen in many parts of the world, recreational users may be interested in Salvia as a legal alternative to illegal drugs. Of course, Salvia is not an appropriate drug for the party scene, given how highly introspective, self-reflective, and otherworldly the experience can be.


The κ-opioid receptor system is linked to a wide array of conditions. This grants salvinorin enormous therapeutic potential, but more human studies are needed. In animal studies, salvinorin A demonstrates anti-anxiety, anti-inflammatory, pain-inhibiting, and antidiarrheal properties

Long-lasting salvinorin A-derived agonists that don’t cross the blood-brain barrier could be a useful treatment approach for a wide variety of peripheral conditions such as irritable bowel syndrome, sciatica, arthritis, and degenerative joint disease. Salvinorin A-derived antagonists could be useful in treating mood disorders, seizures, dementia, schizophrenia, and HIV-related neuropsychiatric disorders.


Salvia Shows Antidepressant Properties

There are clinical reports and case studies that suggest Salvia can be effective in treating depression. In 2001, the psychologist Dr. Karl Hanes published a case report in the Journal of Clinical Psychopharmacology that described the beneficial effects of low dose salvia on intractable depression in his patients. 

He reported that some of his patients would chew small doses of salvia (½-¾ grams of leaf material) 3 times a week and had complete remission from depression, as measured by clinical HAM-D scores. The effects were maintained for at least six months with no signs of relapse or adverse side effects.

Salvinorin A has anti-addictive effects

Salvia has been used for centuries by the Mazatec for treating addiction to alcohol, inhalants, and psychostimulants like cocaine. Relatively recently, research has shed light on how salvinorin A exerts its anti-addictive effects.

Drugs of abuse (psychostimulants and opiates) increase the “feel good” neurotransmitter dopamine in a group of brain regions known as the dopaminergic reward circuitry. Over time, this leads to compulsive drug use and drug-seeking behavior. Salvinorin A has been found to decrease dopamine levels in the reward circuitry. Mechanistically, κ-opioid receptors, the molecular target of Salvia, act in an opposing manner to dopamine in order to maintain homeostasis. 

At a different scale of analysis, addictive behavior results from disruptions in interoception. Interoception refers to the awareness of bodily sensations and how those sensations connect to certain emotional states. Drugs of abuse manipulate interoception by disrupting a cortical region called the insula, a central hub for interoceptive processing. As a result, the insula ‘overvalues’ bodily states associated with the drug and its cues and ‘undervalues’ bodily states while off the drug. Therefore, the drug begins to be the only thing that is pleasurable, resulting in cravings and compulsive drug use.

Human studies by Maqueda and colleagues have demonstrated that salvinorin A profoundly alters interoception by binding with high affinity to the insula. At low doses, salvinorin A increases interoception, making the body feel more safe and trustworthy. At high doses, salvia decreases interoception, making it more difficult to attend to bodily sensations and decreasing awareness of how these sensations are linked to emotional states. In this way, salvinorin A may help to loosen the grip that drugs of abuse have on maladaptive interoceptive processing.

Salvinorin A’s anti-addictive properties have also been established at low doses in animals. One 2009 study found that Salvinorin A reduces cocaine-induced drug-seeking behavior in rats. This was seen as fewer lever presses to self-administer cocaine in a conditioned place preference paradigm. 

As a result of these promising findings, synthetic analogs have been created from salvinorin A that also acts on the κ-opioid receptor system. These potential novel treatments for addiction can be tailored to last longer in the body, potentially alleviating drug use and relapse into drug-seeking. 

Spiritually (Developmentally)

As an entheogenic plant, Salvia opens up dimensions of the psyche that are otherwise inaccessible. Salvia induces visionary states of consciousness in part by inhibiting a part of the brain known as the claustrum. The claustrum connects cortical and subcortical regions and has been called the “conductor of consciousness” by Francis Crick. It is a densely connected structure that integrates various cortical inputs (color, sound touch) into one continuum of experience, rather than layers of singular events. Salvia can, therefore, be an incredibly insightful tool to explore consciousness, leading to significant personal transformation if the insights are attended to and integrated.

Many individuals find that Salvia trips can break down habitual thought patterns and expose old traumas that can be healed. This makes Salvia a potentially effective adjunct to psychotherapeutic practices. Low doses of Salvia can help foster new perspectives, help with attunement to feelings in the body, and enhance one’s connection with nature. In a 2015 interview, the prominent Salvia researcher Daniel Siebert stated, “Salvia is especially useful as a tool for gaining insight and clarity when one feels confused about one’s life path or relationships.” 

Salvia may also be used to enhance spiritual practices as well. In 2000, MAPS (Multidisciplinary Association of Psychedelic Studies) funded research into the use of low dose Salvia as an aid for long-time meditators. Within a group meditation setting, the researchers administered dried leaves in doses ranging from 0.5-2.0 grams. While 0.5g had little effect, the meditators found the 1g dose led to a clearer mind, less distracting thoughts, and easier concentration. The 1.5g and 2g doses were found to be too strong, producing dream-like states and time distortion that inhibited meditation.

7. Salvia Today 

Trends in Use Today

Initially, Salvia’s online visibility and ease of access in the early 2000s created a surge in popularity in the United States and throughout the world. According to the National Survey on Drug Use and Health, the lifetime prevalence of Salvia use grew 83% from 2006 to 2008, from 0.7% to 1.3%. The highest rate of users was between the ages of 18 and 25.

More recently, the trends in salvia use have been decreasing in parallel with legislative bans. From 2009-2015, past year salvia use decreased by 90%

Surveys of college students have shown that salvia remains somewhat of a fringe drug compared to cannabis and the classic psychedelics. In 2008, Lange and colleagues surveyed 1,571 college students and found that 4.4% of them reported using salvia once within the past year. A similar 2008 survey by Khey and colleagues found that only 22.6% of students have ever heard of Salvia divinorum. Among those that have tried it, 51% of them reported they would not try it again. 

Current Studies and Research

At Johns Hopkins University (JHU), Rolland Griffiths and colleagues conducted a study in 2010 on the effects of vaporized salvinorin A in 4 healthy adults. The study examined the subjective and physiological effects of salvinorin A across a wide dose range (0.375 μg/kg to 21 μg/kg). Similar to the classic psychedelics, salvinorin A produced mystical-type experiences, with higher ratings for higher doses. 

This was measured by a 32-item questionnaire (also used in psilocybin trials) called the Mysticism Scale. Interestingly, the researchers found several commonalities in the Salvia experience. In the participants, salvinorin A produced intense vestibular hallucinations, revisitings of childhood memories, cartoon-like imagery, and contact with entities. In addition, the study found salvinorin A to have a safe physiological profile, similar to the findings of previous research. 

A different lab at JHU conducted a study on sublingual salvinorin A. In this study, the researchers administered various doses (250-4000mcg) of sublingual salvinorin A and then measured subjective effects with multiple self-report scales. The researchers found a lack of effect across all doses. They suggest that sublingual bioavailability is low and future studies should use different routes of administration. 

Another ongoing study at JHU is looking into the effects of inhaled salvinorin A on brain function. Researchers are using functional magnetic resonance imaging to characterize brain activity and connectivity of 13 participants. 

At Yale University, an ongoing study is evaluating the effects of salvinorin A in 41 healthy individuals. This study is interested in parsing out the psychotomimetic (psychosis-mimicking) effects of salvinorin A.

Drug Testing Info

Neither basic nor extended drug tests can detect salvinorin A and its metabolites. Currently, salvinorin A can only be detected through the use of specialized lab tests.

Events and More

The American ethnobotanist Daniel Siebert lists Salvia-related events on his website. Daniel Siebert is one of the leading experts on Salvia divinorum, having studied the plant for over twenty years. A wealth of other information on Salvia is available at the link, including podcasts, interviews, scientific articles, experience archives, and much more.

8. Salvia FAQ 

Is Salvia Legal?

Salvia divinorum and salvinorin A are unlisted in the Schedules of the United Nations Drug Conventions. However, many countries have included S. divinorum and salvinorin A in their lists of controlled substances. 

An increasing number of states and countries are considering legislation to ban it. In some countries such as Iceland, Norway, Finland, and Estonia, the plant is controlled under drug legislation. Reference the “Legality” section for a detailed state-wide and international breakdown.

What Does Salvia Do?

Salvia divinorum has been used for centuries as a healing and divinatory herb, producing profound, visionary states of consciousness. Through its effects on the kappa opioid receptor system, the Salvia experience is characterized by ego-dissolution, changes in body ownership, dissociation, visual distortions, vestibular hallucinations, tactile hallucinations, and more.

How Long Does a Salvia Trip Last?

A Salvia trip typically lasts between 5-15 minutes. After effects may then last for an additional 20-40 minutes. Orally-ingested Salvia tends to come up more slowly and last longer, anywhere from 30 minutes to 1.5 hours. 

What Does Salvia Look Like?

Salvia divinorum looks similar to other salvias in the mint family. It can grow to over three feet in height, has hollow square stems, large green leaves, and white flowers with violet calyxes.

How Long Does Salvia Stay in Your System?

Compared to other drugs, Salvinorin A has a short elimination half-life. The detection window is thought to be approximately 12 hours, however, it only shows up on specialized drug tests.

Is Salvia Dangerous?

Salvia divinorum is considered to be low toxicity and without long-term adverse side effects. No fatal overdoses have been reported, and it’s not known to be addictive. The most dangerous aspect of Salvia is improper set and setting. Having an adequately-prepared trip environment (no hazardous objects) and being with a trip sitter is crucial for a safe experience. Salvia should be avoided if there is a history of or predisposition to psychosis.

Where to Buy Salvia?

Depending on regional legality, S. divinorum plants, leaves, leaf extracts, and tinctures can be purchased from internet vendors and head shops. 

Disclaimer: Salvia divinorum is potentially categorized as an illegal drug. Reality Sandwich is not encouraging the use of this drug where it is prohibited. However, we believe that providing information is imperative for the safety of those who choose to explore this substance.  This guide is intended to give educational content and should in no way be viewed as medical recommendations.

RS Contributing Author: Dylan Beard 

Dylan Beard is a freelance science writer and editor based in the beautiful Pacific Northwest. After finishing his physics degree and dabbling in neuroscience research at UC Santa Barbara in 2017, he returned to his first love: writing. As a long-term fan of the human brain, he loves exploring the latest research on psychedelics, nootropics, psychology, consciousness, meditation, and more. When not writing, you can probably find him on hiking trails around Oregon and Washington or listening to podcasts. Feel free to follow him on Insta @dylancb88.

Psychedelic Resources

A Foraging Trip: Where Do Magic Mushrooms Grow?
Eager to learn more about the origin of psilocybin species? Read this article to find out where magic mushrooms grow and more!

How to Make Shroom Tea: Best Recipe and Dosage
A step by step guide on how to brew shroom tea, and why entheogenic psilocybin tea is a preferred method for psychedelic connoisseurs.

R. Gordon Wasson: Author and Mushroom Expert
Learn about R. Gordon Wasson, the “legendary mushroom expert” and popular figure within the psychonaut community.

Shrooms vs Acid: Differences and Similarities Explained
Ever wondered what the differences are between shrooms vs acid, or if you can take both together? This guide explains what you need to know.

Quantum Mechanics, Reality, and Magic Mushrooms
Scientist and author Dr. Chris Becker takes an in-depth approach in understanding how we perceive reality through magic mushrooms and quantum mechanics.

Psilocybin Guide: Effects, Common Uses, Safety
Our ultimate guide to Psilocybin has everything you want to know about this psychedelic fungi from its uses to its legal status.

The Psilocybin Experience: What’s the Deal With Magic Mushrooms?
From microdoses to macrodoses, the psilocybin experience has been sought after both medicinally and recreationally for millennia.

Psilocybin and Magic Mushroom Resources
Curious to learn more about psilocybin? This guide is a comprehensive psilocybin resource containing books, therapeutic studies, and more.

Paul Stamets Profile: Mushroom Guru, Filmmaker, Nutritionist, Scientist
Learn about Paul Stamets, read his thoughts on psilocybin mircodosing, the future of psilocybin, and his recent film “Fantastic Fungi”.

Microdosing Psilocybin & Common Dosage Explained
Microdosing, though imperceivably, is showing to have many health benefits–here is everything you want to know about microdosing psilocybin.

Psilocybin Nasal Spray: Relief for Anxiety, PTSD, and Depression
Microdosing nasal spray with psilocybin, is that possible?! Oregan a start-up Silo Wellness believes so and has created this new option for PTSD treatment.

Mazatec Mushroom Usage: Notes on Approach, Setting and Species for Curious Psilonauts
A look at traditional Mazatec psilocybin mushroom usage, and a comparison to the cliniical therapeutic approach, with an examination of the Mazatec setting and species used in veladas.

María Sabina: The Mazatec Magic Mushroom Woman
Magic mushrooms are incredibly popular today. How they became introduced to into American culture isn’t usually a topic discussed while tripping on psilocybin fungi. We all may have María Sabina to thank for exposing the Western world to the healing properties of the psilocybin mushroom.

Guide to Magic Mushroom Strains
Are there different types of psilocybin? Read our guide to learn about the different magic mushroom strains and their individual effects.

Kilindi Iyi: Mycologist, Traveler, Teacher
Learn about traveler and mycologist Kilindi Iyi known in the psychedelic community for his research and exploration of psilocybin.

How to Store Shrooms: Best Practices
How do you store shrooms for optimal shelf life? Learn how and why the proper storage method is so important.

Shroom Chocolate Recipes: How to Make Magic Mushroom Chocolates
This recipe provides step by step directions on how you can make mushroom chocolates with the necessary ingredients. Read to learn more!

Why Do People Use Psilocybin? New Johns Hopkins Study
Johns Hopkins University School of Medicines has just published a new study on psychoactive effects of psilocybin. Read here to learn more.

How-To Lemon Tek: Ultimate Guide and Recipe
This master guide will teach you how to lemon tek, preventing the onset of negative effects after consuming psilocybin. Read to learn more!

How to Intensify a Mushroom Trip
Learn about techniques like Lemon tekking, or discover the right time to consume cannabis if you are looking to intensify a mushroom trip.

How to Grow Magic Mushrooms: Step-by-Step
This step-by-step guide will show you how to grow magic mushrooms at home. Read this guide before trying it on your own.

How to Dry Magic Mushrooms: Best Practices
Read to learn more about specifics for the best practices on how to dry magic mushrooms after harvesting season.

How to Buy Psilocybin Spores
Interested in psilocybin mushrooms? We’ll walk you through all you need to know to obtain mushroom spores. Nosh on this delish How To guide.

Hippie Flipping: When Shrooms and Molly Meet
What is it, what does it feel like, and how long does it last? Explore the mechanics of hippie flipping and how to safely experiment.

Having Sex on Shrooms: Good or Bad Idea?
Is having sex on shrooms a good idea or an accident waiting to happen? Find out in our guide to sex on magic mushrooms.

Gold Cap Shrooms Guide: Spores, Effects, Identification
Read this guide to learn more about the different characteristics of gold cap mushrooms, and how they differ from other psilocybin species.

Guide to Cooking with Magic Mushrooms
From cookies to smoothies and sandwiches, we cover various methods of cooking with magic mushrooms for the ultimate snack.

2020 Election: The Decriminalize Psilocybin Movement
Are you curious if mushrooms will follow in marijuana’s footsteps? Read to learn about how the U.S. is moving to decriminalize psilocybin.

Oregon’s Initiative to Legalize Mushrooms | Initiative Petition 34
Oregon continues to push ahead with their initiative to legalize Psilocybin in 2020. The measure received its official title and now needs signatures.

Canada Approves Psilocybin Treatment for Terminally-Ill Cancer Patients
Canada’s Minister of Health, Patty Hajdu approved the use of psilocybin to help ease anxiety and depression of four terminal cancer patients.

Mapping the DMT Experience
With only firsthand experiences to share, how can we fully map the DMT experience? Let’s explore what we know about this powerful psychedelic.

Guide to Machine Elves and Other DMT Entities
This guide discusses machine elves, clockwork elves, and other common DMT entities that people experience during a DMT trip.

Is the DMT Experience a Hallucination? 
What if the DMT realm was the real world, and our everyday lives were merely a game we had chosen to play?

How to Store DMT
Not sure how to store DMT? Read this piece to learn the best practices and elements of advice to keep your stuff fresh.

What Does 5-MeO-DMT Show Us About Consciousness?
How does our brain differentiate between what’s real and what’s not? Read to learn what can 5-MeO-DMT show us about consciousness.

How to Smoke DMT: Processes Explained
There are many ways to smoke DMT and we’ve outlined some of the best processes to consider before embarking on your journey.

How to Ground After DMT
Knowing what to expect from a DMT comedown can help you integrate the experience to gain as much value as possible from your journey.

How To Get DMT
What kind of plants contain DMT? Are there other ways to access this psychedelic? Read on to learn more about how to get DMT.

How DMT is Made: Everything You Need to Know
Ever wonder how to make DMT? Read our guide to learn everything you need to know about the procedures of how DMT is made.

Having Sex on DMT: What You Need to Know
Have you ever wondered about sex on DMT? Learn how the God Molecule can influence your intimate experiences.

Does the Human Brain Make DMT? 
With scientific evidence showing us DMT in the brain, what can we conclude it is there for? Read on to learn more.

How to Use DMT Vape Pens
Read to learn all about DMT vape pens including: what to know when vaping, what to expect when purchasing a DMT cartridge, and vaping safely.

DMT Resources
This article is a comprehensive DMT resource providing extensive information from studies, books, documentaries, and more. Check it out!

Differentiating DMT and Near-Death Experiences
Some say there are similarities between a DMT trip and death. Read our guide on differentiating DMT and near-death experiences to find out.

DMT Research from 1956 to the Edge of Time
From a representative sample of a suitably psychedelic crowd, you’d be hard pressed to find someone who couldn’t tell you all about Albert Hofmann’s enchanted bicycle ride after swallowing what turned out to be a massive dose of LSD. Far fewer, however, could tell you much about the world’s first DMT trip.

The Ultimate Guide to DMT Pricing
Check out our ultimate guide on DMT pricing to learn what to expect when purchasing DMT for your first time.

DMT Milking | Reality Sandwich
Indigenous cultures have used 5-MeO-DMT for centuries. With the surge in demand for psychedelic toad milk, is DMT Milking harming the frogs?

Why Does DMT Pervade Nature?
With the presence of DMT in nature everywhere – including human brains – why does it continue to baffle science?

DMT Substance Guide: Effects, Common Uses, Safety
Our ultimate guide to DMT has everything you want to know about this powerful psychedelic referred to as “the spirit molecule”.

DMT for Depression: Paving the Way for New Medicine
We’ve been waiting for an effective depression treatment. Studies show DMT for depression works even for treatment resistant patients.

Beating Addiction with DMT
Psychedelics have been studied for their help overcoming addiction. Read how DMT is helping addicts beat their substance abuse issues.

DMT Extraction: Behind the Scientific Process
Take a look at DMT extraction and the scientific process involved. Learn all you need to know including procedures and safety.

Microdosing DMT & Common Dosages Explained
Microdosing, though imperceivable, is showing to have many health benefits–here is everything you want to know about microdosing DMT.

DMT Art: A Look Behind Visionary Creations
An entire genre of artwork is inspired by psychedelic trips with DMT. Read to learn about the entities and visions behind DMT art.

Changa vs. DMT: What You Need to Know
While similar (changa contains DMT), each drug has its own unique effect and feeling. Let’s compare and contrast changa vs DMT.

5-MeO-DMT Guide: Effects, Benefits, Safety, and Legality
5-Meo-DMT comes from the Sonora Desert toad. Here is everything you want to know about 5-Meo-DMT and how it compares to 4-AcO-DMT.

4-AcO-DMT Guide: Benefits, Effects, Safety, and Legality
This guide tells you everything about 4 AcO DMT & 5 MeO DMT, that belong to the tryptamine class, and are similar but slightly different to DMT.

How Much Does LSD Cost? When shopping around for that magical psychedelic substance, there can be many uncertainties when new to buying LSD. You may be wondering how much does LSD cost? In this article, we will discuss what to expect when purchasing LSD on the black market, what forms LSD is sold in, and the standard breakdown of buying LSD in quantity.   Navy Use of LSD on the Dark Web The dark web is increasingly popular for purchasing illegal substances. The US Navy has now noticed this trend with their staff. Read to learn more.   Having Sex on LSD: What You Need to Know Can you have sex on LSD? Read our guide to learn everything about sex on acid, from lowered inhibitions to LSD users quotes on sex while tripping.   A Drug That Switches off an LSD Trip A pharmaceutical company is developing an “off-switch” drug for an LSD trip, in the case that a bad trip can happen. Some would say there is no such thing.   Queen of Hearts: An Interview with Liz Elliot on Tim Leary and LSD The history of psychedelia, particularly the British experience, has been almost totally written by men. Of the women involved, especially those who were in the thick of it, little has been written either by or about them. A notable exception is Liz Elliot.   LSD Guide: Effects, Common Uses, Safety LSD, Lysergic acid diethylamide, or just acid is one of the most important psychedelics ever discovered. What did history teach us?   Microdosing LSD & Common Dosage Explained Microdosing, though imperceivable, is showing to have many health benefits–here is everything you want to know about microdosing LSD.   LSD Resources Curious to learn more about LSD? This guide includes comprehensive LSD resources containing books, studies and more.   LSD as a Spiritual Aid There is common consent that the evolution of mankind is paralleled by the increase and expansion of consciousness. From the described process of how consciousness originates and develops, it becomes evident that its growth depends on its faculty of perception. Therefore every means of improving this faculty should be used.   Legendary LSD Blotter Art: A Hidden Craftsmanship Have you ever heard of LSD blotter art? Explore the trippy world of LSD art and some of the top artists of LSD blotter art.   LSD and Exercise: Does it Work? LSD and exercise? Learn why high-performing athletes are taking hits of LSD to improve their overall potential.   Jan Bastiaans Treated Holocaust Survivors with LSD Dutch psychiatrist, Jan Bastiaans administered LSD-assisted therapy to survivors of the Holocaust. A true war hero and pioneer of psychedelic-therapy.   LSD and Spiritual Awakening I give thanks for LSD, which provided the opening that led me to India in 1971 and brought me to Neem Karoli Baba, known as Maharajji. Maharajji is described by the Indians as a “knower of hearts.”   How LSD is Made: Everything You Need to Know Ever wonder how to make LSD? Read our guide to learn everything you need to know about the procedures of how LSD is made.   How to Store LSD: Best Practices Learn the best way to store LSD, including the proper temperature and conditions to maximize how long LSD lasts when stored.   Bicycle Day: The Discovery of LSD Every year on April 19th, psychonauts join forces to celebrate Bicycle Day. Learn about the famous day when Albert Hoffman first discovered the effects of LSD.   Cary Grant: A Hollywood Legend On LSD Cary Grant was a famous actor during the 1930’s-60’s But did you know Grant experimented with LSD? Read our guide to learn more.   Albert Hofmann: LSD — My Problem Child Learn about Albert Hofmann and his discovery of LSD, along with the story of Bicycle Day and why it marks a historic milestone.   Babies are High: What Does LSD Do To Your Brain What do LSD and babies have in common? Researchers at the Imperial College in London discover that an adult’s brain on LSD looks like a baby’s brain.   1P LSD: Effects, Benefits, Safety Explained 1P LSD is an analogue of LSD and homologue of ALD-25. Here is everything you want to know about 1P LSD and how it compares to LSD.   Francis Crick, DNA & LSD Type ‘Francis Crick LSD’ into Google, and the result will be 30,000 links. Many sites claim that Crick (one of the two men responsible for discovering the structure of DNA), was either under the influence of LSD at the time of his revelation or used the drug to help with his thought processes during his research. Is this true?   What Happens If You Overdose on LSD? A recent article presented three individuals who overdosed on LSD. Though the experience was unpleasant, the outcomes were remarkably positive.

The Ayahuasca Experience
Ayahuasca is both a medicine and a visionary aid. You can employ ayahuasca for physical, mental, emotional and spiritual repair, and you can engage with the power of ayahuasca for deeper insight and realization. If you consider attainment of knowledge in the broadest perspective, you can say that at all times, ayahuasca heals.


Trippy Talk: Meet Ayahuasca with Sitaramaya Sita and PlantTeachers
Sitaramaya Sita is a spiritual herbalist, pusangera, and plant wisdom practitioner formally trained in the Shipibo ayahuasca tradition.


The Therapeutic Value of Ayahuasca
My best description of the impact of ayahuasca is that it’s a rocket boost to psychospiritual growth and unfolding, my professional specialty during my thirty-five years of private practice.


Microdosing Ayahuasca: Common Dosage Explained
What is ayahuasca made of and what is considered a microdose? Explore insights with an experienced Peruvian brewmaster and learn more about this practice.


Ayahuasca Makes Neuron Babies in Your Brain
Researchers from Beckley/Sant Pau Research Program have shared the latest findings in their study on the effects of ayahuasca on neurogenesis.


The Fatimiya Sufi Order and Ayahuasca
In this interview, the founder of the Fatimiya Sufi Order,  N. Wahid Azal, discusses the history and uses of plant medicines in Islamic and pre-Islamic mystery schools.


Consideration Ayahuasca for Treatment of Post Traumatic Stress Disorder
Research indicates that ayahuasca mimics mechanisms of currently accepted treatments for PTSD. In order to understand the implications of ayahuasca treatment, we need to understand how PTSD develops.


Brainwaves on Ayahuasca: A Waking Dream State
In a study researchers shared discoveries showing ingredients found in Ayahuasca impact the brainwaves causing a “waking dream” state.


Cannabis and Ayahuasca: Mixing Entheogenic Plants
Cannabis and Ayahuasca: most people believe they shouldn’t be mixed. Read this personal experience peppered with thoughts from a pro cannabis Peruvian Shaman.


Ayahuasca Retreat 101: Everything You Need to Know to Brave the Brew
Ayahuasca has been known to be a powerful medicinal substance for millennia. However, until recently, it was only found in the jungle. Word of its deeply healing and cleansing properties has begun to spread across the world as many modern, Western individuals are seeking spiritual, mental, emotional, and physical well-being. More ayahuasca retreat centers are emerging in the Amazon and worldwide to meet the demand.


Ayahuasca Helps with Grief
A new study published in psychopharmacology found that ayahuasca helped those suffering from the loss of a loved one up to a year after treatment.


Ayahuasca Benefits: Clinical Improvements for Six Months
Ayahuasca benefits can last six months according to studies. Read here to learn about the clinical improvements from drinking the brew.


Ayahuasca Culture: Indigenous, Western, And The Future
Ayahuasca has been use for generations in the Amazon. With the rise of retreats and the brew leaving the rainforest how is ayahuasca culture changing?


Ayahuasca Guide: Effects, Common Uses, Safety
The Amazonian brew, Ayahuasca has a long history and wide use. Read our guide to learn all about the tea from its beginnings up to modern-day interest.


Ayahuasca and the Godhead: An Interview with Wahid Azal of the Fatimiya Sufi Order
Wahid Azal, a Sufi mystic of The Fatimiya Sufi Order and an Islamic scholar, talks about entheogens, Sufism, mythology, and metaphysics.


Ayahuasca and the Feminine: Women’s Roles, Healing, Retreats, and More
Ayahuasca is lovingly called “grandmother” or “mother” by many. Just how feminine is the brew? Read to learn all about women and ayahuasca.

What Is the Standard of Care for Ketamine Treatments?
Ketamine therapy is on the rise in light of its powerful results for treatment-resistant depression. But, what is the current standard of care for ketamine? Read to find out.

What Is Dissociation and How Does Ketamine Create It?
Dissociation can take on multiple forms. So, what is dissociation like and how does ketamine create it? Read to find out.

Having Sex on Ketamine: Getting Physical on a Dissociative
Curious about what it could feel like to have sex on a dissociate? Find out all the answers in our guide to sex on ketamine.

Special K: The Party Drug
Special K refers to Ketamine when used recreationally. Learn the trends as well as safety information around this substance.

Kitty Flipping: When Ketamine and Molly Meet
What is it, what does it feel like, and how long does it last? Read to explore the mechanics of kitty flipping.

Ketamine vs. Esketamine: 3 Important Differences Explained
Ketamine and esketamine are used to treat depression. But what’s the difference between them? Read to learn which one is right for you: ketamine vs. esketamine.

Guide to Ketamine Treatments: Understanding the New Approach
Ketamine is becoming more popular as more people are seeing its benefits. Is ketamine a fit? Read our guide for all you need to know about ketamine treatments.

Ketamine Treatment for Eating Disorders
Ketamine is becoming a promising treatment for various mental health conditions. Read to learn how individuals can use ketamine treatment for eating disorders.

Ketamine Resources, Studies, and Trusted Information
Curious to learn more about ketamine? This guide includes comprehensive ketamine resources containing books, studies and more.

Ketamine Guide: Effects, Common Uses, Safety
Our ultimate guide to ketamine has everything you need to know about this “dissociative anesthetic” and how it is being studied for depression treatment.

Ketamine for Depression: A Mental Health Breakthrough
While antidepressants work for some, many others find no relief. Read to learn about the therapeutic uses of ketamine for depression.

Ketamine for Addiction: Treatments Offering Hope
New treatments are offering hope to individuals suffering from addiction diseases. Read to learn how ketamine for addiction is providing breakthrough results.

Microdosing Ketamine & Common Dosages Explained
Microdosing, though imperceivable, is showing to have many health benefits–here is everything you want to know about microdosing ketamine.

How to Ease a Ketamine Comedown
Knowing what to expect when you come down from ketamine can help integrate the experience to gain as much value as possible.

How to Store Ketamine: Best Practices
Learn the best ways how to store ketamine, including the proper temperature and conditions to maximize how long ketamine lasts when stored.

How To Buy Ketamine: Is There Legal Ketamine Online?
Learn exactly where it’s legal to buy ketamine, and if it’s possible to purchase legal ketamine on the internet.

How Long Does Ketamine Stay in Your System?
How long does ketamine stay in your system? Are there lasting effects on your body? Read to discover the answers!

How Ketamine is Made: Everything You Need to Know
Ever wonder how to make Ketamine? Read our guide to learn everything you need to know about the procedures of how Ketamine is made.

Colorado on Ketamine: First Responders Waiver Programs
Fallout continues after Elijah McClain. Despite opposing recommendations from some city council, Colorado State Health panel recommends the continued use of ketamine by medics for those demonstrating “excited delirium” or “extreme agitation”.

Types of Ketamine: Learn the Differences & Uses for Each
Learn about the different types of ketamine and what they are used for—and what type might be right for you. Read now to find out!

Kitty Flipping: When Ketamine and Molly Meet
What is it, what does it feel like, and how long does it last? Read to explore the mechanics of kitty flipping.

MDMA & Ecstasy Guide: Effects, Common Uses, Safety
Our ultimate guide to MDMA has everything you want to know about Ecstasy from how it was developed in 1912 to why it’s being studied today.

How To Get the Most out of Taking MDMA as a Couple
Taking MDMA as a couple can lead to exciting experiences. Read here to learn how to get the most of of this love drug in your relationship.

Common MDMA Dosage & Microdosing Explained
Microdosing, though imperceivable, is showing to have many health benefits–here is everything you want to know about microdosing MDMA.

Having Sex on MDMA: What You Need to Know
MDMA is known as the love drug… Read our guide to learn all about sex on MDMA and why it is beginning to makes its way into couple’s therapy.

How MDMA is Made: Common Procedures Explained
Ever wonder how to make MDMA? Read our guide to learn everything you need to know about the procedures of how MDMA is made.

Hippie Flipping: When Shrooms and Molly Meet
What is it, what does it feel like, and how long does it last? Explore the mechanics of hippie flipping and how to safely experiment.

How Cocaine is Made: Common Procedures Explained
Ever wonder how to make cocaine? Read our guide to learn everything you need to know about the procedures of how cocaine is made.

A Christmas Sweater with Santa and Cocaine
This week, Walmart came under fire for a “Let it Snow” Christmas sweater depicting Santa with lines of cocaine. Columbia is not merry about it.

Ultimate Cocaine Guide: Effects, Common Uses, Safety
This guide covers what you need to know about Cocaine, including common effects and uses, legality, safety precautions and top trends today.

NEWS: An FDA-Approved Cocaine Nasal Spray
The FDA approved a cocaine nasal spray called Numbrino, which has raised suspicions that the pharmaceutical company, Lannett Company Inc., paid off the FDA..

The Ultimate Guide to Cannabis Bioavailability
What is bioavailability and how can it affect the overall efficacy of a psychedelic substance? Read to learn more.

Cannabis Research Explains Sociability Behaviors
New research by Dr. Giovanni Marsicano shows social behavioral changes occur as a result of less energy available to the neurons. Read here to learn more.

The Cannabis Shaman
If recreational and medical use of marijuana is becoming accepted, can the spiritual use as well? Experiential journalist Rak Razam interviews Hamilton Souther, founder of the 420 Cannabis Shamanism movement…

Cannabis Guide: Effects, Common Uses, Safety
Our ultimate guide to Cannabis has everything you want to know about this popular substances that has psychedelic properties.

Cannabis and Ayahuasca: Mixing Entheogenic Plants
Cannabis and Ayahuasca: most people believe they shouldn’t be mixed. Read this personal experience peppered with thoughts from a procannabis Peruvian Shaman.

CBD-Rich Cannabis Versus Single-Molecule CBD
A ground-breaking study has documented the superior therapeutic properties of whole plant Cannabis extract as compared to synthetic cannabidiol (CBD), challenging the medical-industrial complex’s notion that “crude” botanical preparations are less effective than single-molecule compounds.

Cannabis Has Always Been a Medicine
Modern science has already confirmed the efficacy of cannabis for most uses described in the ancient medical texts, but prohibitionists still claim that medical cannabis is “just a ruse.”

Related Posts

Ready to explore the frontiers of consciousness?

Sign up for the Reality Bites newsletter and embark on a journey into the world of psychedelics, mindfulness, and transformation. It’s where the curious minds gather.

Become a conscious agent with us.

Featured Partner

Cosmic Melts

Cosmic Melts are the latest mushroom gummies we’ve been munching on. Choose from five fruity flavors, each gummy containing 350mg of Amanita muscaria.
Amanita muscaria offers a unique (and totally legal!) mushroom experience, and Cosmic Melts is an ideal entry point for the curious consumer.

Our Partners

Discover the transformative power of breathwork: unlock vitality, healing, and self-discovery.

Hear from the RS community in our new video series, spotlighting shared experiences and stories with plant medicines, psychedelics, consciousness, dreams, meditation, etc.

Welcome to Reality Sandwich. Please verify that you are over 18 years of age below.

Reality Sandwich uses cookies to ensure you get the best experience on our website. By entering Reality Sandwich, you are agreeing to the Terms and Conditions and Privacy Policy.